Descriptive epidemiology and phylogenetic analysis of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada, September 2022 to June 2023

Thumbnail image

Download files

DOI

https://doi.org/10.1080/22221751.2024.2392667

Language of the publication
English
Date
2024-09-22
Type
Article
Author(s)
  • Russell, Shannon L.
  • Andrew, Cassandra L.
  • Yang, Kevin C.
  • Coombe, Michelle
  • McGregor, Glenna
  • Redford, Tony
  • Jassem, Agatha N.
  • Zlosnik, James E. A.
  • Giacinti, Jolene
  • Kuchinski, Kevin S.
  • Palmer, John L.
  • Tyson, John R.
  • Fjell, Chris
  • Willie, Megan
  • Ross, Megan V.
  • Winchester, Maeve
  • Wilson, Laurie
  • Berhane, Yohannes
  • Thacker, Caeley
  • Harms, N. Jane
  • Soos, Catherine
  • Burns, Theresa
  • Prystajecky, Natalie
  • Himsworth, Chelsea
Publisher
Taylor & Francis

Abstract

Surveillance data from wildlife and poultry was used to describe the spread of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada from September 2022 – June 2023 compared to the first “wave” of the outbreak in this region, which occurred April – August 2022, after the initial viral introduction. Although the number of HPAI-positive poultry farms and wildlife samples was greater in “Wave 2”, cases were more tightly clustered in southwestern B.C. and the most commonly affected species differed, likely due to an influx of overwintering waterfowl in the area. Eight HPAI genetic clusters, representing seven genotypes and two inter-continental viral incursions, were detected, with significant variation in the relative abundance of each cluster between the waves. Phylogenetic data suggests multiple spillover events from wild birds to poultry and mammals but could not rule out transmission among farms and among mammals.

Subject

  • Animal diseases,
  • Viruses

Keywords

  • Avian influenza,
  • Molecular epidemiology,
  • Whole genome sequencing,
  • Animals--Diseases--Monitoring

Rights

Pagination

1-13

Peer review

Yes

Open access level

Gold

Identifiers

ISSN
2222-1751

Article

Journal title
Emerging Microbes & Infections
Journal volume
13
Journal issue
1
Article number
2392667
Accepted date
2024-08-11
Submitted date
2024-01-18

Citation(s)

Russell, S. L., Andrew, C. L., Yang, K. C., Coombe, M., McGregor, G., Redford, T., Jassem, A. N., Zlosnik, J. E. A., Giacinti, J., Kuchinski, K. S., Palmer, J. L., Tyson, J. R., Fjell, C., Williw, M., Ross, M. V., Winchester, M., Wilson, L., Berhane, Y., Thacker, C., Harms, N. J., Soos, C., Burns, T., Prystajecky, N., & Himsworth, C. (2024). Descriptive epidemiology and phylogenetic analysis of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada, September 2022 to June 2023. Emerging Microbes & Infections, 13(1), Article 2392667. https://doi.org/10.1080/22221751.2024.2392667

Download(s)

URI

Collection(s)

Animals

Full item page

Full item page

Page details

Date modified: