Descriptive epidemiology and phylogenetic analysis of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada, September 2022 to June 2023
- DOI
- Language of the publication
- English
- Date
- 2024-09-22
- Type
- Article
- Author(s)
- Russell, Shannon L.
- Andrew, Cassandra L.
- Yang, Kevin C.
- Coombe, Michelle
- McGregor, Glenna
- Redford, Tony
- Jassem, Agatha N.
- Zlosnik, James E. A.
- Giacinti, Jolene
- Kuchinski, Kevin S.
- Palmer, John L.
- Tyson, John R.
- Fjell, Chris
- Willie, Megan
- Ross, Megan V.
- Winchester, Maeve
- Wilson, Laurie
- Berhane, Yohannes
- Thacker, Caeley
- Harms, N. Jane
- Soos, Catherine
- Burns, Theresa
- Prystajecky, Natalie
- Himsworth, Chelsea
- Publisher
- Taylor & Francis
Abstract
Surveillance data from wildlife and poultry was used to describe the spread of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada from September 2022 – June 2023 compared to the first “wave” of the outbreak in this region, which occurred April – August 2022, after the initial viral introduction. Although the number of HPAI-positive poultry farms and wildlife samples was greater in “Wave 2”, cases were more tightly clustered in southwestern B.C. and the most commonly affected species differed, likely due to an influx of overwintering waterfowl in the area. Eight HPAI genetic clusters, representing seven genotypes and two inter-continental viral incursions, were detected, with significant variation in the relative abundance of each cluster between the waves. Phylogenetic data suggests multiple spillover events from wild birds to poultry and mammals but could not rule out transmission among farms and among mammals.
Subject
- Animal diseases,
- Viruses
Keywords
- Avian influenza,
- Molecular epidemiology,
- Whole genome sequencing,
- Animals--Diseases--Monitoring
Rights
Pagination
1-13
Peer review
Yes
Open access level
Gold
Identifiers
- ISSN
- 2222-1751
Article
- Journal title
- Emerging Microbes & Infections
- Journal volume
- 13
- Journal issue
- 1
- Article number
- 2392667
- Accepted date
- 2024-08-11
- Submitted date
- 2024-01-18
Citation(s)
Russell, S. L., Andrew, C. L., Yang, K. C., Coombe, M., McGregor, G., Redford, T., Jassem, A. N., Zlosnik, J. E. A., Giacinti, J., Kuchinski, K. S., Palmer, J. L., Tyson, J. R., Fjell, C., Williw, M., Ross, M. V., Winchester, M., Wilson, L., Berhane, Y., Thacker, C., Harms, N. J., Soos, C., Burns, T., Prystajecky, N., & Himsworth, C. (2024). Descriptive epidemiology and phylogenetic analysis of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in British Columbia (B.C.) and the Yukon, Canada, September 2022 to June 2023. Emerging Microbes & Infections, 13(1), Article 2392667. https://doi.org/10.1080/22221751.2024.2392667