Multiple wheat genomes reveal global variation in modern breeding

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DOI

https://doi.org/10.1038/s41586-020-2961-x

Language of the publication
English
Date
2020-11-25
Type
Article
Author(s)
  • Walkowiak, Sean
  • Gao, Liangliang
  • Monat, Cecile
  • Haberer, Georg
  • Kassa, Mulualem T.
  • Brinton, Jemima
  • Ramirez-Gonzalez, Ricardo H.
  • Kolodziej, Markus C.
  • Delorean, Emily
  • Thambugala, Dinushika
  • Klymiuk, Valentyna
  • Byrns, Brook
  • Gundlach, Heidrun
  • Bandi, Venkat
  • Siri, Jorge Nunez
  • Nilsen, Kirby
  • Aquino, Catharine
  • Himmelbach, Axel
  • Copetti, Dario
  • Ban, Tomohiro
  • Venturini, Luca
  • Bevan, Michael
  • Clavijo, Bernardo
  • Koo, Dal-Hoe
  • Ens, Jennifer
  • Wiebe, Krystalee
  • N’Diaye, Amidou
  • Fritz, Allen K.
  • Gutwin, Carl
  • Fiebig, Anne
  • Fosker, Christine
  • Fu, Bin Xiao
  • Accinelli, Gonzalo Garcia
  • Gardner, Keith A.
  • Fradgley, Nick
  • Gutierrez-Gonzalez, Juan
  • Halstead-Nussloch, Gwyneth
  • Hatakeyama, Masaomi
  • Koh, Chu Shin
  • Deek, Jasline
  • Costamagna, Alejandro C.
  • Fobert, Pierre
  • Heavens, Darren
  • Kanamori, Hiroyuki
  • Kawaura, Kanako
  • Kobayashi, Fuminori
  • Krasileva, Ksenia
  • Kuo, Tony
  • McKenzie, Neil
  • Murata, Kazuki
  • Nabeka, Yusuke
  • Paape, Timothy
  • Padmarasu, Sudharsan
  • Percival-Alwyn, Lawrence
  • Kagale, Sateesh
  • Scholz, Uwe
  • Sese, Jun
  • Juliana, Philomin
  • Singh, Ravi
  • Shimizu-Inatsugi, Rie
  • Swarbreck, David
  • Cockram, James
  • Budak, Hikmet
  • Tameshige, Toshiaki
  • Tanaka, Tsuyoshi
  • Tsuji, Hiroyuki
  • Wright, Jonathan
  • Wu, Jianzhong
  • Steuernagel, Burkhard
  • Small, Ian
  • Cloutier, Sylvie
  • Keeble-Gagnère, Gabriel
  • Muehlbauer, Gary
  • Tibbets, Josquin
  • Nasuda, Shuhei
  • Melonek, Joanna
  • Hucl, Pierre J.
  • Sharpe, Andrew G.
  • Clark, Matthew
  • Legg, Erik
  • Bharti, Arvind
  • Langridge, Peter
  • Hall, Anthony
  • Uauy, Cristobal
  • Mascher, Martin
  • Krattinger, Simon G.
  • Handa, Hirokazu
  • Shimizu, Kentaro K.
  • Distelfeld, Assaf
  • Chalmers, Ken
  • Keller, Beat
  • Mayer, Klaus F. X.
  • Poland, Jesse
  • Stein, Nils
  • McCartney, Curt A.
  • Spannagl, Manuel
  • Wicker, Thomas
  • Pozniak, Curtis J.
Publisher
Nature

Abstract

Advances in genomics have expedited the improvement of several agriculturally important crops but similar efforts in wheat (Triticum spp.) have been more challenging. This is largely owing to the size and complexity of the wheat genome1, and the lack of genome-assembly data for multiple wheat lines2,3. Here we generated ten chromosome pseudomolecule and five scaffold assemblies of hexaploid wheat to explore the genomic diversity among wheat lines from global breeding programs. Comparative analysis revealed extensive structural rearrangements, introgressions from wild relatives and differences in gene content resulting from complex breeding histories aimed at improving adaptation to diverse environments, grain yield and quality, and resistance to stresses4,5. We provide examples outlining the utility of these genomes, including a detailed multi-genome-derived nucleotide-binding leucine-rich repeat protein repertoire involved in disease resistance and the characterization of Sm16, a gene associated with insect resistance. These genome assemblies will provide a basis for functional gene discovery and breeding to deliver the next generation of modern wheat cultivars.

Subject

  • Agriculture

Keywords

  • Wheat -- Breeding,
  • Blé -- Amélioration,
  • Plant genomes

Rights

Pagination

277-283

Peer review

Yes

Open access level

Gold

Identifiers

ISSN
1476-4687
0028-0836

Article

Journal title
Nature
Journal volume
588
Accepted date
2020-09-09
Submitted date
2020-04-03

Citation(s)

Walkowiak, S., Gao, L., Monat, C., Haberer, G., Kassa, M. T., Brinton, J., Ramirez-Gonzalez, R. H., Kolodziej, M. C., Delorean, E., Thambugala, D., Klymiuk, V., Byrns, B., Gundlach, H., Bandi, V., Siri, J. N., Nilsen, K., Aquino, C., Himmelbach, A., Copetti, D., Ban, T., Venturini, L., Bevan, M., Clavijo, B., Koo, D.-H., Ens, J., Wiebe, K., N'Diaye, A., Fritz, A. K., Gutwin, C., Fiebig, A., Fosker, C., Fu, B. X., Accinelli, G. G., Gardner, K. A., Fradgley, N., Gutierrez-Gonzalez, J., Halstead-Nussloch, G., Hatakeyama, M., Koh, C. S., Deek, J., Costamagna, A. C., Fobert, P., Heavens, D., Kanamori, H., Kawaura, K., Kobayashi, F., Krasileva, K., Kuo, T., McKenzie, N., Murata, K., Nabeka, Y., Paape, T., Padmarasu, S., Percival-Alwyn, L., Kagale, S., Scholz, U., Sese, J., Juliana, P., Singh, R., Shimizu-Inatsugi, R., Swarbreck, D., Cockram, J., Budak, H., Tameshige, T., Tanaka, T., Tsuji, H., Wright, J., Wu, J., Steuernagel, B., Small, I., Cloutier, S., Keeble-Gagnère, G., Muehlbauer, G., Tibbets, J., Nasuda, S., Melonek, J., Hucl, P. J., Sharpe, A. G., Clark, M., Legg, E., Bharti, A., Langridge, P., Hall, A., Uauy, C., Mascher, M., Krattinger, S. G., Handa, H., Shimizu, K. K., Distelfeld, A., Chalmers, K., Keller, B., Mayer, K. F. X., Poland, J., Stein, N., McCartney, C. A., Spannagl, M., Wicker, T., & Pozniak C. J. (2020). Multiple wheat genomes reveal global variation in modern breeding. Nature, 588, 277-283. https://doi.org/10.1038/s41586-020-2961-x

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