Neonatal abstinence syndrome hospitalizations in Canada: a descriptive study

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creativework.keywords - en
Neonatal abstinence syndrome
Opioids
Canada
Neonatal withdrawal
Pregnancy
Maternal substance use
dc.contributor.author
Plouffe, Rebecca
Grywacheski, Vera
Luo, Wei
Nelson, Chantal
Orpana, Heather
dc.date.accessioned
2023-06-02T11:52:05Z
dc.date.available
2023-06-02T11:52:05Z
dc.date.issued
2023-04
dc.description.abstract - en
Objective The objective of this paper is to describe the trend of newborn hospitalizations with neonatal abstinence syndrome (NAS) in Canada, between 2010 and 2020, and to examine severity indicators for these hospitalizations. Methods National hospitalization data (excluding Quebec) from the Canadian Institute for Health Information’s Discharge Abstract Database, from January 2010 to March 2021, and Statistics Canada’s Vital Statistics Birth Database were used. Analyses were performed to examine NAS hospitalizations by year and quarter, and by severity indicators of length of stay, Special Care Unit admission and status upon discharge. Severity indicators were further stratified by gestational age at birth. Results An increasing number and rate of NAS hospitalizations in Canada between 2010 (n = 1013, 3.5 per 1000 live births) and 2020 (n = 1755, 6.3 per 1000 live births) were identified. A seasonal pattern was observed, where rates of NAS were lowest from April to June and highest from October to March. Mean length of stay in acute inpatient care was approximately 15 days and 71% of NAS hospitalizations were admitted to the Special Care Unit. Hospitalizations for pre-term births with NAS had longer durations and greater rates of Special Care Unit admissions compared to term births with NAS. Conclusion The number and rate of NAS hospitalizations in Canada increased during the study, and some infants required a significant amount of specialized healthcare. Additional research is required to determine what supports and education for pregnant people can reduce the incidence of NAS hospitalizations.
dc.identifier.citation
Plouffe R, Grywacheski V, Luo W, Nelson C, Orpana H. Neonatal abstinence syndrome hospitalizations in Canada: a descriptive study. Can J Public Health. 2023 Apr;114(2):277-286. doi: 10.17269/s41997-022-00726-5
dc.identifier.doi
https://doi.org/10.17269/s41997-022-00726-5
dc.identifier.uri
https://open-science.canada.ca/handle/123456789/510
dc.language.iso
en
dc.publisher
Springer
dc.rights - en
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.rights - fr
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.rights.uri - en
https://creativecommons.org/licenses/by/4.0/
dc.rights.uri - fr
https://creativecommons.org/licenses/by/4.0/deed.fr
dc.subject - en
Health
dc.subject - fr
Santé
dc.subject.en - en
Health
dc.subject.fr - fr
Santé
dc.title - en
Neonatal abstinence syndrome hospitalizations in Canada: a descriptive study
dc.type - en
Article
dc.type - fr
Article
local.article.journalissue
2
local.article.journaltitle
Canadian Journal of Public Health
local.article.journalvolume
114
local.pagination
277–286
local.peerreview - en
Yes
local.peerreview - fr
Oui
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