Three separate acquisitions of blaNDM-1 in three different bacterial species from a single patient
Three separate acquisitions of blaNDM-1 in three different bacterial species from a single patient
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Full item details
- creativework.keywords - en
- Carbapenemases
- Canada
- New Delhi metallo-beta-lactamase
- Pseudomonas
- Acientobacter
- Proteus
- dc.contributor.author
- Mataseje, L. F.
- Pitout, J.
- Croxen, M.
- Mulvey, M. R.
- Dingle, T. C.
- dc.date.accessioned
- 2023-11-17T22:57:39Z
- dc.date.available
- 2023-11-17T22:57:39Z
- dc.date.issued
- 2023-09-09
- dc.description.abstract - en
- To investigate the acquisition and relatedness of New Delhi Metallo-beta-lactamase among multiple separate species from one patient. Five isolates from three species (Pseudomonas aeruginosa; Pa, Acinetobacter baumannii; Ab and Proteus mirabilis; Pm) suspected of harbouring a carbapenemase were investigated by phenotype (antimicrobial susceptibilities) and whole genome sequencing. Epidemiological data was collected on this patient. Three different carbapenemase genes were detected; blaVIM-1 (Pa; ST773), blaOXA-23 (Ab, ST499) and blaNDM-1 identified in all isolates. NDM regions were found chromosomally integrated in all isolates. Data showed no evidence of NDM-1 transfer within this patient suggesting the enzyme was acquired in three separate events.
- dc.identifier.citation
- Mataseje, L. F., Pitout, J., Croxen, M., Mulvey, M. R., & Dingle, T. C. (2023). Three separate acquisitions of blaNDM-1 in three different bacterial species from a single patient. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 42(10), 1275–1280. https://doi.org/10.1007/s10096-023-04651-4
- dc.identifier.doi
- https://doi.org/10.1007/s10096-023-04651-4
- dc.identifier.issn
- 0934-9723
- dc.identifier.other
- PMC10511597
- dc.identifier.pubmedID
- 37688673
- dc.identifier.uri
- https://open-science.canada.ca/handle/123456789/1306
- dc.language.iso
- en
- dc.publisher
- Springer Nature
- dc.rights - en
- Creative Commons Attribution 4.0 International (CC BY 4.0)
- dc.rights - fr
- Creative Commons Attribution 4.0 International (CC BY 4.0)
- dc.rights.openaccesslevel - en
- Gold
- dc.rights.openaccesslevel - fr
- Or
- dc.rights.uri - en
- https://creativecommons.org/licenses/by/4.0/
- dc.rights.uri - fr
- https://creativecommons.org/licenses/by/4.0/deed.fr
- dc.subject - en
- Health
- dc.subject - fr
- Santé
- dc.subject.en - en
- Health
- dc.subject.fr - fr
- Santé
- dc.title - en
- Three separate acquisitions of blaNDM-1 in three different bacterial species from a single patient
- dc.type - en
- Article
- dc.type - fr
- Article
- local.article.journalissue
- 10
- local.article.journaltitle
- European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
- local.article.journalvolume
- 42
- local.pagination
- 1275-1280
- local.peerreview - en
- Yes
- local.peerreview - fr
- Oui
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