Temporal trends and determinants of COVID-19 vaccine series initiation after recent pregnancy
Temporal trends and determinants of COVID-19 vaccine series initiation after recent pregnancy
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Full item details
- creativework.keywords - en
- COVID-19
- COVID-19 vaccination
- COVID-19 vaccine series initiation
- Pregnancy
- Pregnant
- Birth
- dc.contributor.author
- Török, Eszter
- Shinsa, Tavleen
- Dimanlig-Cruz, Sheryll
- Alton, Gillian D.
- Sprague, Ann E.
- Dunn, Sandra I.
- Shah, Prakesh S.
- El-Chaâr, Darine
- Regan, Annette K.
- Wilson, Kumanan
- Buchan, Sarah A.
- Kwong, Jeffrey C.
- Håberg, Siri E.
- Gravel, Christopher A.
- Okun, Nannette
- Walker, Mark C.
- MacDonald, Shannon E.
- Wilson, Sarah E.
- Barrett, Jon
- Fell, Deshayne B.
- dc.date.accessioned
- 2024-02-02T16:35:29Z
- dc.date.available
- 2024-02-02T16:35:29Z
- dc.date.issued
- 2023-05-30
- dc.description.abstract - en
- During the rapid deployment of COVID-19 vaccines in 2021, safety concerns may have led some pregnant individuals to postpone vaccination until after giving birth. This study aimed to describe temporal patterns and factors associated with COVID-19 vaccine series initiation after recent pregnancy in Ontario, Canada. Using the provincial birth registry linked with the COVID-19 vaccine database, we identified all individuals who gave birth between January 1 and December 31, 2021, and had not yet been vaccinated by the end of pregnancy, and followed them to June 30, 2022 (follow-up ranged from 6 to 18 months). We used cumulative incidence curves to describe COVID-19 vaccine initiation after pregnancy and assessed associations with sociodemographic, pregnancy-related, and health behavioral factors using Cox proportional hazards regression to estimate adjusted hazard ratios (aHR) and 95% confidence intervals (CI). Among 137,198 individuals who gave birth in 2021, 87,376 (63.7%) remained unvaccinated at the end of pregnancy; of these, 65.0% initiated COVID-19 vaccination by June 30, 2022. Lower maternal age (<25 vs. 30–34 y aHR: 0.73, 95%CI: 0.70–0.77), smoking during pregnancy (vs. nonsmoking aHR: 0.68, 95%CI: 0.65–0.72), lower neighborhood income (lowest quintile vs. highest aHR: 0.79, 95%CI: 0.76–0.83), higher material deprivation (highest quintile vs. lowest aHR: 0.74, 95%CI: 0.70–0.79), and exclusive breastfeeding (vs. other feeding aHR: 0.81, 95%CI: 0.79–0.84) were associated with lower likelihood of vaccine initiation. Among unvaccinated individuals who gave birth in 2021, COVID-19 vaccine initiation after pregnancy reached 65% by June 30, 2022, suggesting persistent issues with vaccine hesitancy and/or access to vaccination in this population.
- dc.identifier.citation
- Eszter Török, Tavleen Dhinsa, Dimanlig-Cruz S, et al. Temporal trends and determinants of COVID-19 vaccine series initiation after recent pregnancy. PubMed Central. 2023;19(2). doi:https://doi.org/10.1080/21645515.2023.2215150
- dc.identifier.doi
- 10.1080/21645515.2023.2215150
- dc.identifier.issn
- 2164-5515
- dc.identifier.uri
- https://open-science.canada.ca/handle/123456789/1926
- dc.language.iso
- en
- dc.publisher
- Taylor & Francis
- dc.rights - en
- Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
- dc.rights - fr
- Creative Commons Attribution - Pas d'utilisation commerciale - Pas de modification 4.0 International (CC BY-NC-ND 4.0)
- dc.rights.openaccesslevel - en
- Gold
- dc.rights.openaccesslevel - fr
- Or
- dc.rights.uri - en
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- dc.rights.uri - fr
- https://creativecommons.org/licenses/by-nc-nd/4.0/deed.fr
- dc.subject - en
- Health
- dc.subject - fr
- Santé
- dc.subject.en - en
- Health
- dc.subject.fr - fr
- Santé
- dc.title - en
- Temporal trends and determinants of COVID-19 vaccine series initiation after recent pregnancy
- dc.type - en
- Article
- dc.type - fr
- Article
- local.acceptedmanuscript.articlenum
- 2215150
- local.article.journalissue
- 2
- local.article.journaltitle
- Human Vaccines & Immunotherapeutics
- local.article.journalvolume
- 19
- local.peerreview - en
- Yes
- local.peerreview - fr
- Oui
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