Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada

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DOI

https://doi.org/10.1111/irv.13186

Language of the publication
English
Date
2023-08
Type
Article
Author(s)
  • Zinszer, Kate
  • Charland, Katia
  • Pierce, Laura
  • Saucier, Adrien
  • Hamelin, Marie-Ève
  • Da Torre, Margot Barbosa
  • Carbonneau, Julie
  • Nguyen, Cat Tuong
  • De Serres, Gaston
  • Papenburg, Jesse
  • Boivin, Guy
  • Quach, Caroline
Publisher
Influenza and Other Respiratory Viruses

Abstract

The EnCORE study is a prospective serology study of SARS-CoV-2 in a cohort of children from Montreal, Canada. Based on data from our fourth round of data collection (May–October 2022), we estimated SARS-CoV-2 seroprevalence and seroconversion. Using multivariable regression, we identified factors associated with seroconversion. Our results show that previously seronegative children were approximately 9–12 times more likely to seroconvert during the early Omicron-dominant period compared to pre-Omicron rounds. Unlike the pre-Omicron rounds, the adjusted rate of seroconversion among 2- to 4-year-olds was higher than older age groups. As seen previously, higher seroconversion rates were associated with ethnic/racial minority status.

Subject

  • Health

Keywords

  • SARS‐CoV‐2,
  • Canada,
  • adolescents,
  • children,
  • seroconversion,
  • seroprevalence

Rights

Peer review

Yes

Identifiers

PubMed ID
37638094
ISSN
1750-2659

Article

Journal title
Influenza and Other Respiratory Viruses
Journal volume
17
Journal issue
8
Article number
e13186

Sponsors

Funding for this study was provided by thePublic Health Agency of Canada through theCOVID-19 Immunity Task Force to Dr Zinszer

Citation(s)

Zinszer K, Charland K, Pierce L, Saucier A, Hamelin MÈ, Da Torre MB, Carbonneau J, Nguyen CT, De Serres G, Papenburg J, Boivin G, Quach C. Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada. Influenza Other Respir Viruses. 2023 Aug 25;17(8):e13186. doi: 10.1111/irv.13186

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Public health surveillance

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