Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada
- DOI
- Language of the publication
- English
- Date
- 2023-08
- Type
- Article
- Author(s)
- Zinszer, Kate
- Charland, Katia
- Pierce, Laura
- Saucier, Adrien
- Hamelin, Marie-Ève
- Da Torre, Margot Barbosa
- Carbonneau, Julie
- Nguyen, Cat Tuong
- De Serres, Gaston
- Papenburg, Jesse
- Boivin, Guy
- Quach, Caroline
- Publisher
- Influenza and Other Respiratory Viruses
Abstract
The EnCORE study is a prospective serology study of SARS-CoV-2 in a cohort of children from Montreal, Canada. Based on data from our fourth round of data collection (May–October 2022), we estimated SARS-CoV-2 seroprevalence and seroconversion. Using multivariable regression, we identified factors associated with seroconversion. Our results show that previously seronegative children were approximately 9–12 times more likely to seroconvert during the early Omicron-dominant period compared to pre-Omicron rounds. Unlike the pre-Omicron rounds, the adjusted rate of seroconversion among 2- to 4-year-olds was higher than older age groups. As seen previously, higher seroconversion rates were associated with ethnic/racial minority status.
Subject
- Health
Keywords
- SARS‐CoV‐2,
- Canada,
- adolescents,
- children,
- seroconversion,
- seroprevalence
Rights
Peer review
Yes
Identifiers
- PubMed ID
- 37638094
- ISSN
- 1750-2659
Article
- Journal title
- Influenza and Other Respiratory Viruses
- Journal volume
- 17
- Journal issue
- 8
- Article number
- e13186
Sponsors
Funding for this study was provided by thePublic Health Agency of Canada through theCOVID-19 Immunity Task Force to Dr Zinszer
Citation(s)
Zinszer K, Charland K, Pierce L, Saucier A, Hamelin MÈ, Da Torre MB, Carbonneau J, Nguyen CT, De Serres G, Papenburg J, Boivin G, Quach C. Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada. Influenza Other Respir Viruses. 2023 Aug 25;17(8):e13186. doi: 10.1111/irv.13186