Ku-gaa-gii pimitizi-win, the COVID-19 cohort study of people experiencing homelessness in Toronto, Canada: a study protocol
Ku-gaa-gii pimitizi-win, the COVID-19 cohort study of people experiencing homelessness in Toronto, Canada: a study protocol
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- dc.contributor.author
- Richard, Lucie
- Nisenbaum, Rosane
- Liu, Michael
- McGeer, Allison
- Mishra, Sharmistha
- Gingras, Anne-Claude
- Gommerman, Jennifer L.
- Sniderman, Ruby
- Pedersen, Cheryl
- Spandier, Olivia
- Jenkinson, Jesse I. R.
- Baral, Stefan
- Mejia-Lancheros, Cilia
- Agarwal, Arnav
- Jamal, Alainna J.
- Ostrowski, Mario
- Dhalla, Irfan
- Stewart, Suzanne
- Gabriel, Mikaela
- Brown, Michael
- Hester, Joe
- Hwang, Stephen W.
- dc.date.accessioned
- 2024-01-12T17:43:19Z
- dc.date.available
- 2024-01-12T17:43:19Z
- dc.date.issued
- 2022-08-05
- dc.description.abstract - en
- INTRODUCTION: Initial reports suggest people experiencing homelessness (PEH) are at high risk for SARS-CoV-2 infection and associated morbidity and mortality. However, there have been few longitudinal evaluations of the spread and impact of COVID-19 among PEH. This study will estimate the prevalence and incidence of COVID-19 infections in a cohort of PEH followed prospectively in Toronto, Canada. It will also examine associations between individual-level and shelter-level characteristics with COVID-19 infection, adverse health outcomes related to infection and vaccination. Finally, the data will be used to develop and parameterise a mathematical model to characterise SARS-CoV-2 transmission dynamics, and the transmission impact of interventions serving PEH. DESIGN, METHODS AND ANALYSIS: Ku-gaa-gii pimitizi-win will follow a random sample of PEH from across Toronto (Canada) for 12 months. 736 participants were enrolled between June and September 2021, and will be followed up at 3-month intervals. At each interval, specimens (saliva, capillary blood) will be collected to determine active SARS-CoV-2 infection and serologic evidence of past infection and/or vaccination, and a detailed survey will gather self-reported information, including a detailed housing history. To examine the association between individual-level and shelter-level characteristics on COVID-19-related infection, adverse outcomes, and vaccination, shelter and healthcare administrative data will be linked to participant study data. Healthcare administrative data will also be used to examine long-term (up to 5 years) COVID-19-related outcomes among participants. ETHICS AND DISSEMINATION: Ethical approval was obtained from the Unity Health Toronto and University of Toronto Health Sciences Research Ethics Boards (# 20-272). Ku-gaa-gii pimitizi-win was designed in collaboration with community and service provider partners and people having lived experience of homelessness. Findings will be reported to groups supporting Ku-gaa-gii pimitizi-win, Indigenous and other community partners and service providers, funding bodies, public health agencies and all levels of government to inform policy and public health programs.
- dc.identifier.doi
- https://doi.org/10.1136/bmjopen-2022-063234
- dc.identifier.issn
- 2044-6055
- dc.identifier.uri
- https://open-science.canada.ca/handle/123456789/1755
- dc.language.iso
- en
- dc.publisher
- British Medical Journal Publishing Group
- dc.rights - en
- Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)
- dc.rights - fr
- Creative Commons Attribution-Pas d’Utilisation Commerciale 4.0 International (CC BY-NC 4.0)
- dc.rights.openaccesslevel - en
- Gold
- dc.rights.openaccesslevel - fr
- Or
- dc.rights.uri - en
- https://creativecommons.org/licenses/by-nc/4.0/
- dc.rights.uri - fr
- https://creativecommons.org/licenses/by-nc/4.0/deed.fr
- dc.subject - en
- Health
- dc.subject - fr
- Santé
- dc.subject.en - en
- Health
- dc.subject.fr - fr
- Santé
- dc.title - en
- Ku-gaa-gii pimitizi-win, the COVID-19 cohort study of people experiencing homelessness in Toronto, Canada: a study protocol
- dc.type - en
- Article
- dc.type - fr
- Article
- local.acceptedmanuscript.articlenum
- e063234
- local.article.journaltitle
- BMJ Open
- local.article.journalvolume
- 12
- local.pagination
- 1-8, 1
- local.peerreview - en
- Yes
- local.peerreview - fr
- Oui
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