Accuracy of self-reported COVID-19 vaccination status compared with a public health vaccination registry in Québec : observational diagnostic study

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dc.contributor.author
Archambault, Patrick M.
Rosychuk, Rhonda J.
Audet, Martyne
Bola, Rajan
Vatanpour, Shabnam
Brooks, Steven C.
Daoust, Raoul
Clark, Gregory
Grant, Lars
Vaillancourt, Samuel
Welsford, Michelle
Morrison, Laurie J.
Hohl, Corinne M.
Canadian COVID-19 Emergency Department Rapid Response Network (CCEDRRN) investigators
Network of Canadian Emergency Researchers
Canadian Critical Care Trials Group
dc.date.accessioned
2025-02-06T15:50:05Z
dc.date.available
2025-02-06T15:50:05Z
dc.date.issued
2023-06-16
dc.description.abstract - en
<p>Background: The accuracy of self-reported vaccination status is important to guide real-world vaccine effectiveness studies and policy making in jurisdictions where access to electronic vaccine registries is restricted.</p> <p>Objective: This study aimed to determine the accuracy of self-reported vaccination status and reliability of the self-reported number of doses, brand, and time of vaccine administration.</p> <p>Methods: This diagnostic accuracy study was completed by the Canadian COVID-19 Emergency Department Rapid Response Network. We enrolled consecutive patients presenting to 4 emergency departments (EDs) in Québec between March 24, 2020, and December 25, 2021. We included adult patients who were able to consent, could speak English or French, and had a proven COVID-19 infection. We compared the self-reported vaccination status of the patients with their vaccination status in the electronic Québec Vaccination Registry. Our primary outcome was the accuracy of the self-reported vaccination status (index test) ascertained during telephone follow-up compared with the Québec Vaccination Registry (reference standard). The accuracy was calculated by dividing all correctly self-reported vaccinated and unvaccinated participants by the sum of all correctly and incorrectly self-reported vaccinated and unvaccinated participants. We also reported interrater agreement with the reference standard as measured by unweighted Cohen κ for self-reported vaccination status at telephone follow-up and at the time of their index ED visit, number of vaccine doses, and brand.</p> <p>Results: During the study period, we included 1361 participants. At the time of the follow-up interview, 932 participants reported at least 1 dose of a COVID-19 vaccine. The accuracy of the self-reported vaccination status was 96% (95% CI 95%-97%). Cohen κ for self-reported vaccination status at phone follow-up was 0.91 (95% CI 0.89-0.93) and 0.85 (95% CI 0.77-0.92) at the time of their index ED visit. Cohen κ was 0.89 (95% CI 0.87-0.91) for the number of doses, 0.80 (95% CI 0.75-0.84) for the brand of the first dose, 0.76 (95% CI 0.70-0.83) for the brand of the second dose, and 0.59 (95% CI 0.34-0.83) for the brand of the third dose.</p> <p>Conclusions: We reported a high accuracy of self-reported vaccination status for adult patients without cognitive disorders who can express themselves in English or French. Researchers can use self-reported COVID-19 vaccination data on the number of doses received, vaccine brand name, and timing of vaccination to guide future research with patients who are capable of self-reporting their vaccination data. However, access to official electronic vaccine registries is still needed to determine the vaccination status in certain susceptible populations where self-reported vaccination data remain missing or impossible to obtain.</p> <p>Trial Registration: Clinicaltrials.gov NCT04702945; https://clinicaltrials.gov/ct2/show/NCT04702945</p>
dc.description.sponsorship
This network was funded by the Canadian Institutes of Health Research (447679, 464947, and 466880); Ontario Ministry of Colleges and Universities (C-655-2129); Saskatchewan Health Research Foundation (5357); Genome BC (COV024 and VAC007); Fondation du CHU de Québec (Octroi No. 4007); and Sero-Surveillance and Research (COVID-19 Immunity Task Force Initiative), who provided peer-reviewed funding. The BC Academic Health Science Network and BioTalent Canada provided non–peer-reviewed funding.
dc.identifier.doi
https://doi.org/10.2196/44465
dc.identifier.issn
2369-2960
dc.identifier.pubmedID
37327046
dc.identifier.uri
https://open-science.canada.ca/handle/123456789/3399
dc.language.iso
en
dc.publisher - en
JMIR Publications
dc.rights - en
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.rights - fr
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.rights.uri - en
https://creativecommons.org/licenses/by/4.0/
dc.rights.uri - fr
https://creativecommons.org/licenses/by/4.0/deed.fr
dc.subject - en
Health
Coronavirus diseases
Immunization
dc.subject - fr
Santé
Maladie à coronavirus
Immunisation
dc.subject.en - en
Health
Coronavirus diseases
Immunization
dc.subject.fr - fr
Santé
Maladie à coronavirus
Immunisation
dc.title - en
Accuracy of self-reported COVID-19 vaccination status compared with a public health vaccination registry in Québec : observational diagnostic study
dc.type - en
Article
dc.type - fr
Article
local.acceptedmanuscript.articlenum
e44465
local.article.journaltitle - en
JMIR Public Health and Surveillance
local.article.journalvolume
9
local.pagination
1-15
local.peerreview - en
Yes
local.peerreview - fr
Oui
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