Clarifying winter clean heating importance : insight chemical compositions and cytotoxicity exposure to primary and aged pollution emissions in China rural areas

Sun, Jian; Niu, Xinyi; Zhang, Bin; Zhang, Leiming; Yu, Jinjin; He, Kun; Zhang, Tian; Wang, Qiyuan; Xu, Hongmei; Cao, Junji; Shen, Zhenxing

doi:https://open-science.canada.ca/handle/123456789/3174

Clarifying winter clean heating importance : insight chemical compositions and cytotoxicity exposure to primary and aged pollution emissions in China rural areas

Simple item page

Full item details

dc.contributor.author: Sun, Jian; Niu, Xinyi; Zhang, Bin; Zhang, Leiming; Yu, Jinjin; He, Kun; Zhang, Tian; Wang, Qiyuan; Xu, Hongmei; Cao, Junji; Shen, Zhenxing
dc.date.accepted: 2022-07-19
dc.date.accessioned: 2024-11-25T19:20:32Z
dc.date.available: 2024-11-25T19:20:32Z
dc.date.issued: 2022-10-15
dc.date.submitted: 2022-05-13
dc.description.abstract - en: Residential solid fuel combustion (RSFC) is an important source of PM2.5. Here we investigate the cytotoxicity of primarily emitted and photochemically aged PM2.5 to A549 cells. Owing to the formation of water-soluble ions and organics (e.g., oPAHs and nPAHs), emission factors of PM2.5 were increased by 44.4% on average after 7-day equivalent photochemical aging, which greatly altered chemical profiles of freshly emitted PM2.5. Consequently, the cytotoxicity varied with aging duration that 2-day and 7-day aged PM2.5 induced 22.5% and 35.1%, respectively, higher levels of reactive oxygen species than primary emissions. Similar increases were also observed for multi-cytotoxicity. Correlation analysis and western blot results collectively confirmed HO-1/Nrf-2 signaling pathway dominated the cytotoxicity of aged PM2.5 from RSFC, which was regulated by the enhanced o-PAHs and n-PAHs during photochemical aging. Thus, aged and secondary aerosol exposure needs to be paid more attention due to the enhanced cytotoxicity and the vast crowd involved.
dc.identifier.issn: 1095-8630; 0301-4797
dc.identifier.uri: https://open-science.canada.ca/handle/123456789/3174
dc.language.iso: en
dc.publisher - en: Elsevier
dc.relation.isreplacedby: https://doi.org/10.1016/j.jenvman.2022.115822
dc.relation.replaces: https://open-science.canada.ca/handle/123456789/2341
dc.rights - en: Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
dc.rights - fr: Creative Commons Attribution - Pas d'utilisation commerciale - Pas de modification 4.0 International (CC BY-NC-ND 4.0)
dc.rights.openaccesslevel - en: Green
dc.rights.openaccesslevel - fr: Vert
dc.rights.uri - en: https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.uri - fr: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.fr
dc.subject - en: Fuels; Heating; Atmospheric emissions
dc.subject - fr: Combustible; Chauffage; Émissions atmosphériques
dc.subject.en - en: Fuels; Heating; Atmospheric emissions
dc.subject.fr - fr: Combustible; Chauffage; Émissions atmosphériques
dc.title - en: Clarifying winter clean heating importance : insight chemical compositions and cytotoxicity exposure to primary and aged pollution emissions in China rural areas
dc.type - en: Accepted manuscript
dc.type - fr: Manuscrit accepté
local.acceptedmanuscript.articlenum: 115822
local.article.journaltitle - en: Journal of Environmental Management
local.article.journalvolume: 320
local.pagination: 54 pages
local.peerreview - en: Yes
local.peerreview - fr: Oui

Download(s)

Original bundle

Now showing 1 - 1 of 1

Name: ClarifyingWinterCleanHeatingImportanceInsightChemicalCompositionsCytotoxicityExposurePrimaryAgedPollutionEmissionsChinaRuralAreasAccepted.pdf

Size: 3.1 MB

Format: PDF

Download file

Collection(s)

Air