Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada

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creativework.keywords - en
SARS‐CoV‐2
Canada
adolescents
children
seroconversion
seroprevalence
dc.contributor.author
Zinszer, Kate
Charland, Katia
Pierce, Laura
Saucier, Adrien
Hamelin, Marie-Ève
Da Torre, Margot Barbosa
Carbonneau, Julie
Nguyen, Cat Tuong
De Serres, Gaston
Papenburg, Jesse
Boivin, Guy
Quach, Caroline
dc.date.accessioned
2023-12-22T13:55:12Z
dc.date.available
2023-12-22T13:55:12Z
dc.date.issued
2023-08
dc.description.abstract-fosrctranslation - en
The EnCORE study is a prospective serology study of SARS-CoV-2 in a cohort of children from Montreal, Canada. Based on data from our fourth round of data collection (May–October 2022), we estimated SARS-CoV-2 seroprevalence and seroconversion. Using multivariable regression, we identified factors associated with seroconversion. Our results show that previously seronegative children were approximately 9–12 times more likely to seroconvert during the early Omicron-dominant period compared to pre-Omicron rounds. Unlike the pre-Omicron rounds, the adjusted rate of seroconversion among 2- to 4-year-olds was higher than older age groups. As seen previously, higher seroconversion rates were associated with ethnic/racial minority status.
dc.description.sponsorship
Funding for this study was provided by thePublic Health Agency of Canada through theCOVID-19 Immunity Task Force to Dr Zinszer
dc.identifier.citation
Zinszer K, Charland K, Pierce L, Saucier A, Hamelin MÈ, Da Torre MB, Carbonneau J, Nguyen CT, De Serres G, Papenburg J, Boivin G, Quach C. Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada. Influenza Other Respir Viruses. 2023 Aug 25;17(8):e13186. doi: 10.1111/irv.13186
dc.identifier.doi
https://doi.org/10.1111/irv.13186
dc.identifier.issn
1750-2659
dc.identifier.pubmedID
37638094
dc.identifier.uri
https://open-science.canada.ca/handle/123456789/1364
dc.language.iso
en
dc.publisher
Influenza and Other Respiratory Viruses
dc.rights - en
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.rights - fr
Creative Commons Attribution 4.0 International (CC BY 4.0)
dc.rights.uri - en
https://creativecommons.org/licenses/by/4.0/
dc.rights.uri - fr
https://creativecommons.org/licenses/by/4.0/deed.fr
dc.subject - en
Health
dc.subject - fr
Santé
dc.subject.en - en
Health
dc.subject.fr - fr
Santé
dc.title - en
Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada
dc.type - en
Article
dc.type - fr
Article
local.acceptedmanuscript.articlenum
e13186
local.article.journalissue
8
local.article.journaltitle
Influenza and Other Respiratory Viruses
local.article.journalvolume
17
local.peerreview - en
Yes
local.peerreview - fr
Oui
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