Higher contact among vaccinated can be a mechanism for negative vaccine effectiveness
Higher contact among vaccinated can be a mechanism for negative vaccine effectiveness
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Full item details
- dc.contributor.author
- Bodner, Korryn
- Knight, Jesse
- Hamilton, Mackenzie A.
- Mishra, Sharmistha
- dc.date.accessioned
- 2025-01-29T19:55:23Z
- dc.date.available
- 2025-01-29T19:55:23Z
- dc.date.issued
- 2022-05-13
- dc.description.abstract - en
- Evidence from early observational studies suggested negative vaccine effectiveness for the SARS-CoV-2 Omicron variant. Using transmission modeling, we illustrated how increased contact between vaccinated individuals, vaccinated contact heterogeneity, paired with lower vaccine efficacies could produce negative measurements and how we can identify this mechanism via a key temporal signature.
- dc.description.sponsorship
- This study was funded by the Canada COVID-19 Immunity Task Force grant
- dc.identifier.doi
- https://doi.org/10.1101/2022.04.25.22274266
- dc.identifier.uri
- https://open-science.canada.ca/handle/123456789/3379
- dc.language.iso
- en
- dc.publisher - en
- medRxiv
- dc.rights - en
- Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
- dc.rights - fr
- Creative Commons Attribution - Pas d'utilisation commerciale - Pas de modification 4.0 International (CC BY-NC-ND 4.0)
- dc.rights.openaccesslevel - en
- Green
- dc.rights.openaccesslevel - fr
- Vert
- dc.rights.uri - en
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- dc.rights.uri - fr
- https://creativecommons.org/licenses/by-nc-nd/4.0/deed.fr
- dc.subject - en
- Health
- Coronavirus diseases
- Immunization
- Modelling
- dc.subject - fr
- Santé
- Maladie à coronavirus
- Immunisation
- Modélisation
- dc.subject.en - en
- Health
- Coronavirus diseases
- Immunization
- Modelling
- dc.subject.fr - fr
- Santé
- Maladie à coronavirus
- Immunisation
- Modélisation
- dc.title - en
- Higher contact among vaccinated can be a mechanism for negative vaccine effectiveness
- dc.type - en
- Submitted manuscript
- dc.type - fr
- Manuscrit soumis
- local.pagination
- 1-9
- local.peerreview - en
- No
- local.peerreview - fr
- Non
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